Avaliação físico-química e capacidade antioxidante do extrato de buriti (Mauritia flexuosa L.) e atividade antitumoral em linhagem celular de câncer de mama MDA-MB-231 / Physico-chemical evaluation and antioxidant capacity of buriti extract and antitumor activity in breast cancer cell line MDA-MB-231

Mariana Silva Pelosi, Iris Leite, Luan Passos, Christian Ferreira, Armando Ubirajara Oliveira Sabaa-Srur, Eliane Fialho

Abstract


O buriti (Mauritia flexuosa L.) é um fruto de origem do Amazonas e Cerrado/Brasil, matéria-prima com elevada capacidade antioxidante de interesse para o desenvolvimento de novos produtos e rico em nutrientes e compostos bioativos associados à prevenção de doenças crônicas não transmissíveis. O objetivo do trabalho foi analisar, na polpa do buriti, a composição centesimal, teor de sólidos solúveis, pH, coordenadas colorimétricas, carotenoides, compostos fenólicos totais e capacidade antioxidante por DPPH, FRAP e TEAC. Células tumorais de mama (MDA-MB-231) foram incubadas com diferentes concentrações do extrato da polpa do buriti e avaliou-se a viabilidade celular e a capacidade antioxidante celular (CAC). A polpa de buriti apresentou 11,35 °Brix, pH 3,8 e valores de L* 38,79, a* 16,11 e b* 27,07 relacionados aos pigmentos naturais responsáveis pela cor alaranjada do fruto. É um fruto rico em lipídeos, com 11,90 g / 100 g de peso fresco, VET de 153,60 Kcal / 100g e se destaca pelo elevado teor de carotenoides, sendo 82,5 % β-caroteno. O buriti é rico em compostos fenólicos totais e apresentou elevada capacidade antioxidante. Nas condições experimentais testadas, não foi observada alteração na viabilidade celular ou CAC.


Keywords


Mauritia flexuosa L., valor nutricional, células MDA-MB-231, capacidade antioxidante, capacidade antioxidante celular.

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DOI: https://doi.org/10.34117/bjdv6n4-064

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