Medicamentos inovadores para a pediatria: uma revisão da literatura / Innovative medicines for pediatrics: a review of the literature

Jéssica de Oliveira Mussel, Adriana Silveira Pereira de Melo, Marcia Maria Barros dos Passos, Mariana Sato de Souza Bustamante Monteiro

Abstract


Os pacientes pediátricos compõem um grupo heterogêneo e apresenta diversos desafios para os profissionais de saúde. Dentre eles está a escassez de medicamentos próprios para a pediatria, devido a diversos fatores que dificultam a Pesquisa e Desenvolvimento de novos medicamentos para este público, que como consequência, gera uma baixa adesão a algumas terapias medicamentosas. O objetivo deste trabalho foi identificar nas literaturas recentes novas formas farmacêuticas que atendam às necessidades do público pediátrico. Foi realizada uma revisão da literatura nas bases de dados PubMed, Science Direct, SciELO e Lilacs, no período de 2010 a 2021, utilizando as palavras chave “pediatric dosage forms”, “pediatric adherence”, “pediatric compliance”. Foram encontradas alternativas às formas farmacêuticas clássicas, como por exemplo: sistemas que simulam alimentos, como gelatinas, chocolates, pirulitos e gomas de mascar e formas impressas em três dimensões. As formas farmacêuticas que simulam alimentos apresentam como vantagem: semelhança visual e organoléptica com doces já conhecidos pelas crianças. Por sua vez, os sistemas impressos em três dimensões já contam com um representante incluído na Farmacopeia Americana e se destacam como uma inovação promissora, devido à possibilidade de serem produzidos utilizando qualquer geometria.

 


Keywords


Pediatria, Inovações Farmacotécnicas, Tecnologia Farmacêutica.

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DOI: https://doi.org/10.34117/bjdv7n7-222

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