Hancornia speciosa extract presents antimicrobial action against Pseudomonas aeruginosa and Staphylococcus aureus Extract shows antimicrobial activity / O extracto de Hancornia speciosa apresenta acção antimicrobiana contra Pseudomonas aeruginosa e Staphylococcus aureus O extracto mostra actividade antimicrobiana

Afonso Celso Silva Dórea, Daniela Droppa- Almeida, Alice de Alencar Santos, Lívia Maria do Amorim Costa Gaspar, Glenda Amaral da Silva, Lumar Lucena Alves, Francine Ferreira Padilha

Abstract


Aims: To evaluate the preliminary phytochemical profile of the leaf and fruit ethanolic extracts of Hancornia speciosa Gomes, as well as its antimicrobial and anti-biofilm activities.

Methods and Results:  Samples of the leaves and fruits of H. speciosa Gomes, collected in the city of Estância, Sergipe state, Brazil, were used to obtain the extract. Each material was macerated in 96% alcohol and submitted to the ultrasonic bath. The extracts showed effectiveness against gram positive and Gram-negative planktonic bacteria, where the leaves presented better results, with a minimum inhibitory concentration (MIC) of 0.625 mg.ml-1 against hospital Staphylococcus aureus, and 1.25 mg.ml-1 against the standard strain of this species. Regarding the percentage of inhibition of biofilms, leaf extract remained more efficient, although the effects were quite varied, strongly dependent on the individual features of each lineage.

 Conclusions:  The provided data demonstrate that crude extracts were able to inhibit some multi-resistant microorganisms.

Significance and Impact of Study: This study evaluated another potential pharmacological property of the extract of Hancornia speciosa Gomes, in a context of dissemination bacterial multiresistance, which demands the discovery of new alternative methods for the treatment of infections.


Keywords


Biofilms, Bioproducts, Antimicrobials, Staphylococci, Pseudomonads.

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DOI: https://doi.org/10.34117/bjdv.v7i5.29980

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