Non-invasive monitoring of intracranial pressure during midazolam-induced moderate sedation for upper gastrointestinal endoscopy / Monitoramento não invasivo da pressão intracraniana durante a sedação moderada induzida por midazolam para endoscopia digestiva alta

Bianca Drewnowsk, Rafael Nastas Acras, Cristiane Rickli, Mariana Schechtel Koch, Bruna França Bueno, Robson Schimandeiro Novak, José Carlos Rebuglio Vellosa

Abstract


Midazolam is a drug chosen for moderate sedation by many endoscopists, it acts on receptors of the cortex, thalamus and cerebellum to produce the sedation effect, and its effects on intracranial pressure during moderate sedation have been poorly studied. This report provided data on intracranial pressure monitoring before, during sedation application, during upper digestive endoscopy and after examination. From this collected data we evaluated intracranial pressure through its wave morphology and P2/P1 ratio. A small reduction in this last parameter was observed after the exam and may be related to midazolam use. It is suggested this must be investigated in further studies.

 


Keywords


Midazolam, Moderate Sedation, Intracranial Pressure, Brain Compliance, Non-Invasive Monitoring.

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DOI: https://doi.org/10.34117/bjdv.v7i5.29327

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