Arbovirus in transplants of solid organs and eyeball: High risk in endemic area receptors? / Arbovírus em transplantes de órgãos sólidos e globo ocular: Alto risco em receptores de áreas endêmicas?

Lilian Carla Carneiro, Paulo Alex Neves da Silva

Abstract


This work is a retrospective cross-sectional analytical study that evaluated individuals transplanted from solid organs and eye balls that had infection by the Chikungunya or Zika virus and, received the organ from an asymptomatic donor. An epidemiological assessment of infection by the Chikungunya and Zika virus in Brazil, was also carried out, and an assessment of the organ and eyeball transplant situation in Brazil. Other data were obtained from the literature, carrying out a survey of articles published in the PUBMED database, from January 2015 to December 2019, which released data from case reports and retrospective and prospective studies. The symptoms most frequently associated with CHIKV are myalgia (60% - 93%), fever above 38.9 ºC (90%) and asymptomatic cases (16% -27%), which are not as frequent, but are relevant when it comes to transplants. Symptoms and signs generally associated with Zika virus infection are skin rashes (91%), fever above 38.9º C (65% -80%), in addition to asymptomatic (80%). We found that recipients of organs contaminated with CHIKV or ZIKV may have different outcomes depending on the transplanted organ. Through this evidence, people who had a recent infection or death from these arboviruses could be candidates for kidney and liver donation.


Keywords


Chikungunya, Zika, Transplantation, kidney, Liver

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DOI: https://doi.org/10.34117/bjdv7n2-169

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