Morphological evaluation of macrophage infected with Toxoplasma Gondii / Avaliação morfológica de macrófagos infectados com Toxoplasma Gondii

Authors

  • Gabriella Oliveira Alves Moreira de Carvalho Brazilian Journals Publicações de Periódicos, São José dos Pinhais, Paraná
  • Olga Maria de Jesus Souza
  • Maria Rita do Nascimento Kiffer
  • Tiago Alexandre Silva Nascimento
  • Thiago Manchester de Mello
  • Regina Coeli dos Santos Goldenberg
  • Sérgio Henrique Seabra
  • Fabio da Silva de Azevedo Fortes

DOI:

https://doi.org/10.34117/bjdv7n1-273

Keywords:

Macrophages, J774G8 cell line, cell culture, Toxoplasma gondii.

Abstract

O Toxoplasma gondii é o parasita causador da toxoplasmose, doença negligenciada que ainda carece de estudos que visem elucidar a relação entre a parasitemia e o sistema imunológico. Uma das principais células do sistema imunológico são os macrófagos e estes possuem linhagens celulares imortalizadas que fornecem um modelo de estudo acessível para experimentos in vitro . Com isso, este trabalho pretende enfatizar a importância da linhagem de macrófagos J774G8 em estudos com protozoários, destacando a viabilidade e alterações morfológicas da cultura de células infectadas com Toxoplasma gondii .

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Published

2021-01-20

How to Cite

de Carvalho, G. O. A. M., Souza, O. M. de J., Kiffer, M. R. do N., Nascimento, T. A. S., de Mello, T. M., Goldenberg, R. C. dos S., Seabra, S. H., & Fortes, F. da S. de A. (2021). Morphological evaluation of macrophage infected with Toxoplasma Gondii / Avaliação morfológica de macrófagos infectados com Toxoplasma Gondii. Brazilian Journal of Development, 7(1), 4035–4050. https://doi.org/10.34117/bjdv7n1-273

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Original Papers