O papel de alguns micro-organismos na carcinogênese / The role of some microorganisms in carcinogenesis

Édila Vilela Ribeiro, Marcelo Moreno, Micheline de Azevedo Lima, Celidarque da Silva Dias, Kalinka Zuleika da Silva Dias, Maísa Freire Cartaxo Pires de Sá, Davi Antas e Silva

Abstract


A associação de alguns microrganismos envolvidos diretamente com o processo de carcinogênese vem aumentando a cada dia. A inflamação crônica causada por esses micróbios, além de fatores relacionados ao hospedeiro e ao ambiente, são fatores importantes para a iniciação do câncer. Muitos patógenos têm sido classificados como cancerígenos para os seres humanos, tais como: Helicobacter pylori, Vírus da hepatite B, vírus da hepatite C e o papilomavírus humano. O estudo teve como objetivo realizar uma revisão bibliográfica sobre o papel destes micro-organismos na carcinogênese, assim como estudar os mecanismos utilizados por esses patógenos no processo de geração do câncer. Foi possível observar que alguns fatores de virulências presentes nesses microrganismos são de fundamental importância no desenvolvimento da doença, tais como a cag A e Vac A da Helicobacter pylori.


Keywords


Carcinogênese, Micro-organismos, Câncer

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DOI: https://doi.org/10.34117/bjdv6n9-258

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