COVID-19 e a infecção por SARS-CoV-2 em um panorama geral/ COVID-19 and infection by SARS-CoV-2 in an overview
DOI:
https://doi.org/10.34119/bjhrv3n2-182Keywords:
pandemia, virologia, teste laboratorialAbstract
Objetivo: Frente ao quadro pandêmico vivido em 2020 no mundo, este trabalho de revisão tem por objetivo, formar e informar através da literatura o panorama geral do quadro de COVID-19 Métodos: Para tal, foram selecionados aspectos de caracterização, etiologia, patogenia, quadro clínico, laboratorial, de imagem e principais medidas tomadas para realização do combate a infecção do COVID019. Revisão Bibliográfica: Sabendo que o vírus SARS-CoV-2 causador do quadro patológico, a revisão focou nos aspectos da gestante, passando pelo nascituro, crianças, adultos e idosos com apanhado geral das informações pertinentes a cada faixa etária. A descrição de quadros clínicos e a mimetização com demais quadros apresentados por afecções de vias respiratórias superiores e inferiores e demais doenças sazoanais, junto com seu diagnostico laboratorial com alterações e anormalidades, exames de imagens e tomadas de decisões a partir dos resultados. Apresentado ainda, processo de tratamento, vacinas e investigações cientificas. Para finalizar os dados encontrados, ações de promoção de saúde capazes de melhorar a qualidade de vida de toda população. Conclusão: O trabalho demonstrou extrema importância devido a sua abordagem ampla da pandemia por coronavírus e como identificá-la, trazendo uma forma simples e descomplicada, levando conhecimento cientifico a população e informações verídicas e de qualidade.
References
BARON SA, et al. Teicoplanin: an alternative drug for the treatment of coronavirus COVID-19? Int. J. Antimicrobial Agents. 2020; 105944. https://doi.org/10.1016/j.ijantimicag.2020.105944.
BEDFORD J, et al. COVID-19: towards controlling of a pandemic. The Lancet 0, 2020. https://doi.org/10.1016/S0140-6736(20)30673-5.
BERGER ZD, et al. Covid-19: control measures must be equitable and inclusive. BMJ, 2020, 368. https://doi.org/10.1136/bmj.m1141.
BRUCE EA, et al. (2020). Rt-qPCR detection of Sars-CoV-2 Rna from patient nasopharyngeal swab using qiagen rneasy kits or directly via omission of an rna extraction step. BioRxiv 2020.03.20.001008. https://doi.org/10.1101/2020.03.20.001008.
CAO B. et al. A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19New England Journal of Medicine. 2020. https://doi.org/10.1056/NEJMoa2001282.
CORTEGIAN, A. et al. A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19. 2020. Journal of Critical Care. https://doi.org/10.1016/j.jcrc.2020.03.005.
DE LUCA, D. Managing neonates with respiratory failure due to SARS-CoV-2. Lancet Child Adolesc Health, 2020; 4, e8. https://doi.org/10.1016/S2352-4642(20)30073-0.
FAN Q, et al. Anal swab findings in an infant with COVID-19. Pediatric Investigation, 2020; 4, 48–50. https://doi.org/10.1002/ped4.12186.
GAO Y, et al. Diagnostic Utility of Clinical Laboratory Data Determinations for Patients with the Severe COVID-19. Journal of Medical Virology, 2020; n/a. https://doi.org/10.1002/jmv.25770.
GAUTRET P, et al. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. International Journal Antimicrobial Agents, 20202; 105949. https://doi.org/10.1016/j.ijantimicag.2020.105949.
GURWITZ D. Angiotensin receptor blockers as tentative SARS-CoV-2 therapeutics. Drug Development Research. 2020; https://doi.org/10.1002/ddr.21656.
HOFFMANN M, et al. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor. Cell, 2020; 0. https://doi.org/10.1016/j.cell.2020.02.052.
HSUEH PR, et al. Chronological evolution of IgM, IgA, IgG and neutralisation antibodies after infection with SARS-associated coronavirus. Clinical Microbiology and Infection., 2020; 10, 1062–1066. https://doi.org/10.1111/j.1469-0691.2004.01009.x
JOOB B, WIWANITKIT VCOVID-19 can present with a rash and be mistaken for Dengue. Journal of the American Academy of Dermatology . 2020, 0. https://doi.org/10.1016/j.jaad.2020.03.036.
JUNIOR S DE A, et al. Bases pedagógicas em curso profissionalizante de Farmácia e Laboratório Clínico como apoio na construção profissional do indivíduo. Revista Eletrônica Acervo Saúde. 2019. e649–e649. https://doi.org/10.25248/reas.e649.2019.
JUNIOR S DE A, et al. Biosafety evaluation and characterization of occupational risks in a ready care unit paulista, Brazil. Research, Society and Development. 2020, 9, 74922028. https://doi.org/10.33448/rsd-v9i2.2028.
KHAN SPL, et al Impact of COVID-19 infection on pregnancy outcomes and the risk of maternal-to-neonatal intrapartum transmission of COVID-19 during natural birth. Infection Control & Hospital Epidemiology 1–9. https://doi.org/10.1017/ice.2020.84.
KIM JY, et al. Viral Load Kinetics of SARS-CoV-2 Infection in First Two Patients in Korea. J. Korean Med. Sci. 2020, 35, e86. https://doi.org/10.3346/jkms.2020.35.e86.
LEBER AL ,et al. Multicenter Evaluation of BioFire FilmArray Respiratory Panel 2 for Detection of Viruses and Bacteria in Nasopharyngeal Swab Samples. Journal of Clinical Microbiology. 2018;. 56. https://doi.org/10.1128/JCM.01945-17.
LI Y, XIA L. Coronavirus Disease 2019 (COVID-19): Role of Chest CT in Diagnosis and Management. American Journal of Roentgenology, 2020; 1–7. https://doi.org/10.2214/AJR.20.22954.
LI Q., et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus–Infected Pneumonia. New England Journal of Medicine. 2020. https://doi.org/10.1056/NEJMoa2001316.
LI, Y, et al. Insight into COVID-2019 for pediatricians. Pediatric Pulmonology n/a. https://doi.org/10.1002/ppul.24734.
LIPPI G, PLEBANI M. Laboratory abnormalities in patients with COVID-2019 infection. Clinical Chemistry and Laboratory Medicine (CCLM). 2020. https://doi.org/10.1515/cclm-2020-0198.
LIU J, et al. Hydroxychloroquine, a less toxic derivative of chloroquine, is effective in inhibiting SARS-CoV-2 infection in vitro. Cell Discovery. 2020; 6, 1–4. https://doi.org/10.1038/s41421-020-0156-0.
LÜERS JC, et al. [The Covid-19 pandemic and otolaryngology: What it comes down to?]. Laryngorhinootologie. 2020. https://doi.org/10.1055/a-1095-2344.
LUNG J, et al. The potential chemical structure of anti-SARS-CoV-2 RNA-dependent RNA polymerase. Journal of Medical Virology. 2020. https://doi.org/10.1002/jmv.25761.
MATTHAY MA, et al. Treatment for severe acute respiratory distress syndrome from COVID-19. The Lancet Respiratory Medicine 0, 2020. https://doi.org/10.1016/S2213-2600(20)30127-2.
NIUD Y, Xu F. Deciphering the power of isolation in controlling COVID-19 outbreaks. The Lancet Global Health 8, e452–e453. 2020. https://doi.org/10.1016/S2214-109X(20)30085-1.
ONG E, et al. COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning. BioRxiv 2020.03.20.000141. 2020. https://doi.org/10.1101/2020.03.20.000141.
PARMET WE, SINHA MS. Covid-19 — The Law and Limits of Quarantine. New England Journal of Medicine 0, null. 2020. https://doi.org/10.1056/NEJMp2004211.
PRACHAR M, et al. COVID-19 Vaccine Candidates: Prediction and Validation of 174 SARS-CoV-2 Epitopes. BioRxiv 2020.03.20.000794. 2020. https://doi.org/10.1101/2020.03.20.000794.
RODRIGUEZ-MORALES, et al. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Medicine and Infectious Disease 101623. 2020. https://doi.org/10.1016/j.tmaid.2020.101623.
SAHRAEI Z, et al. Aminoquinolines Against Coronavirus Disease 2019 (COVID-19): Chloroquine or Hydroxychloroquine. Int. J. Antimicrob. Agents 105945. 2020. https://doi.org/10.1016/j.ijantimicag.2020.105945.
WALLS AC, et al. Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein. Cell. 2020. https://doi.org/10.1016/j.cell.2020.02.058.
WHITWORTH J. COVID-19: a fast evolving pandemic. Trans. R. Soc. The American Journal of Tropical Medicine and Hygiene, 2020. https://doi.org/10.1093/trstmh/traa025.
WHO; Organization WH. Coronavirus. Disponível em: https://www.who.int/emergencies/diseases/novel-coronavirus-2019. Acesso em: 30 mar. 2020.
WILLAN J, et al. Challenges for NHS hospitals during covid-19 epidemic. BMJ 368. 2020. https://doi.org/10.1136/bmj.m1117.
DE WIT E, et al. SARS and MERS: recent insights into emerging coronaviruses. Nature Reviews Microbiology, 2016; 14, 523–534. https://doi.org/10.1038/nrmicro.2016.81.
XU H, et al. High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa. International Journal of Oral Science, 2020; 12, 1–5. https://doi.org/10.1038/s41368-020-0074-x.
XU XW, et al. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series. BMJ 2020; 368, m606. https://doi.org/10.1136/bmj.m606.
ZEINALIAN M, et al. A potential protective role of Losartan against coronavirus induced lung damage. Infection Control & Hospital Epidemiology 1–6. https://doi.org/10.1017/ice.2020.80.
ZHANG R, et al. COVID-19: Melatonin as a potential adjuvant treatment. Life Sci. 2020; 117583. https://doi.org/10.1016/j.lfs.2020.117583.
ZHOU Z, et al. Effect of gastrointestinal symptoms on patients infected with COVID-19. Gastroenterology 2020; S0016508520303620. https://doi.org/10.1053/j.gastro.2020.03.020.