Healing bio compound for the treatment of fissures in the diabetic foot / Biocomposto cicatrizante para o tratamento de fissuras no pé diabético

Lusinalva Leonardo Da Silva, Licínio Esmeraldo Silva, Patrícia De Fátima Lopes, Heloísa Werneck De Macedo


Xerosis cutis in Mellitus diabetes is a common complication that if not treated can cause fissures, infections, ulcer and its prevention is fundamental. Herbal medicine has been contributing for the improvement of the healing process. The objective of this study was to analyze the therapeutic efficacy of a bio compound of essential oils for the treatment of xerosis cutis and fissures in the feet of diabetic patients in order to prevent upcoming complications. The studies were developed in Nova Friburgo, Brazil, with 47 diabetic adult patients with xerosis cutis and fissures in their feet, they were divided into two groups: CG (control n=22) treated with urea cream 10% and SG (study n=25) treated with the bio compound. The fissures were measured (length X width) and photographed every week. Measurement of the glycated hemoglobin: in the beginning of the treatment and 60 days later. Therapeutic efficacy: decreased measures of the fissures; lack of complications (pain, bleeding and increase of the fissure area); healing time. The average of the decrease of the fissure area was alike. The complete healing of the fissure occurred: 52.9% in SG and 47.1% in CG. There was no significant difference in the decrease of the fissure in the patients with total healing. Time for healing: SG took in average 11.6 weeks and CG 12 weeks (non-significant difference). Product efficacy: 60% in SG and 36.4% in CG reported some recovery right in the first seven days. All patients reported recovery in the healing of the fissures and xerosis cutis. In SG all reported no pain, itch, burn sensation or edema in their legs or feet after the treatment with the bio compound, and in CG only 33.3% of them reported some recovery in local pain and no one of them reported any recovery in the edema in their legs or feet. The bio compound was efficient for the treatment of fissures and xerosis cutis in the feet of diabetic patients, providing hydration, skin recovery, absence of pain, itch, and decrease of edema, being indicated as an advantage for the treatment of fissures and xerosis cutis, regardlessly the glycemic level.


treatment, diabetes, xerosis cutis, healing, fissures.


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DOI: https://doi.org/10.34119/bjhrv2n6-091


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