Efeito protetor do treino aeróbico em ratos submetidos à dieta hiperlipídica e normolipídica mensurados pela análise do perfil lipídico e do processo inflamatório tecidual / Protective effect of aerobic training in rats submitted to hyperlipidic and normolipidic diets measured by the analysis of lipid profile and tissue inflammatory process

Alan José Barbosa Magalhães, José Carlos Silva Camargo Filho, José Ricardo Lenzi Mariolani, Regina Celi Trindade Camargo, Sergio Minoru Oikawa, William Dias Belangero

Abstract


Objetivo: Avaliar o efeito protetor do treino aeróbico em ratos submetidos a dieta hiperlipídica e padrão levando-se em consideração o ganho da massa corporal, o acúmulo do tecido adiposo visceral e o perfil lipídico sérico. Métodos: Trinta e seis ratos machos Wistar foram divididos nos grupos Dieta Padrão e Dieta Hiperlipídica, cada grupo com subgrupos sedentário e treinados com o mesmo protocolo aeróbico. O consumo calórico foi medido semanalmente. O colesterol total e os triglicerídeos séricos foram medidos na fase pré-treino, 8ª e 13ª semana. Logo após a eutanásia foi mensurada a massa corporal, dosada a lipoproteína de alta densidade (HDL), coletado o tecido adiposo para cálculo do percentual relativo à massa corporal e o músculo sóleo para análise morfométrica. Na análise estatística foram utilizados os Teste Kruskall-Wallis e Wilcoxon, adotando p<0,05. Resultados: Sem gerar diferenças nas massas corporal e do sóleo entre os subgrupos (p>0,05), o treino aeróbico reduziu o colesterol total em ambos os grupos (p<0,05). No grupo Hiperlipídico, o treino aeróbico aumentou o trofismo muscular (p<0,05). No grupo Padrão, o treino aeróbico aumentou o HDL, diminuiu o tecido adiposo relativo e a inflamação muscular (p<0,05). O grupo Hiperlipídico apresentou menor consumo calórico, maior nível de triglicerídeos séricos e maior quantidade de tecido adiposo total e relativo comparado ao grupo Padrão (p<0,05). Conclusão: O treino aeróbico reduziu o colesterol total em ambos os grupos, gerou hipertrofia muscular no grupo Hiperlipídico e reduziu o tecido adiposo relativo, a inflamação muscular e aumentou o HDL no grupo Padrão.


Keywords


Exercício Físico, Músculo Esquelético, Gordura Intra-Abdominal, Triglicerídeos, Colesterol HDL.

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DOI: https://doi.org/10.34119/bjhrv4n2-369

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