Desordens gastrointestinais associadas à infecção pelo sars-CoV-2: síntese de evidências / Gastrointestinal disorders associated with sars-CoV-2 infection: summary of evidence

Josiel Neves da Silva, Raissa Santos Reimann, Jéssica Nobre Andrade, Vinícius Santos Romão, Ivan Gregório Ivankovics

Abstract


Introdução: Os primeiros casos da COVID-19, causada pela infecção do novo coronavírus (SARS-CoV-2), surgiram na China, em dezembro de 2019. Apesar da porta de entrada mais comum do agente etiológico ser pelo trato respiratório, evidências demonstram que a doença pode apresentar sintomas extrapulmonares, como os do trato gastrointestinal. Objetivo: Descrever as desordens gastrointestinais associadas à infecção pelo coronavírus. Método: Estudo de caráter exploratório, baseado no método de revisão bibliográfica, envolvendo artigos publicados entre 2019 e julho de 2020 na plataforma PubMed, encontrados pelas seguintes palavras-chave: “gastrointestinal disorders associated to COVID-19”, por meio das quais foram selecionados 26 artigos que se adequavam ao tema. Resultados: Os distúrbios gastrointestinais mais prevalentes são náuseas, vômitos, anorexia e diarreia. Porém, disfunções hepáticas também são comuns, principalmente em pacientes idosos e graves. Além disso, há relatos de pancreatite aguda secundária à COVID-19. E quanto a complicações intestinais, foram encontrados dois relatos de pneumatose intestinal. Conclusão: Embora ainda não esteja totalmente esclarecido se os sintomas gastrointestinais indicam maior viremia ou um processo fisiopatológico alternativo, observa-se que a presença destes configuram um fator de risco para a maior severidade da doença.

 

 


Keywords


SARS-CoV-2, COVID-19, Desordens Gastrointestinais.

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DOI: https://doi.org/10.34119/bjhrv4n2-246

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