A eficácia da fibrina rica em plaquetas em exodontias de terceiros molares inferiores: uma revisão da literatura / The efficacy of fibrin-rich platelets in extractions of lower third molars: a literature review

Gabriel Carvalho Matos, Raissa Pinheiro Moraes, Thiago Jonathan Silva dos Santos, Eduardo Costa Studart Soares, Fábio Wildson Gurgel Costa

Abstract


Introdução: A remoção dos terceiros molares mandibulares é um dos procedimentos cirúrgicos mais comumente realizados na Odontologia, entretanto, é frequentemente acompanhada por complicações, sendo a dor, trismo e edema as mais comumente relatadas. Nesse contexto, a Fibrina Rica em Plaquetas (PRF), tem sido utilizada em diversos procedimentos cirúrgicos devido aos seus benefícios ne redução da morbidade pós operatória. Apresenta-se como uma das alternativas mais promissoras de fonte autóloga de citocinas e fatores de crescimento capazes de favorecer a regeneração tecidual. Objetivo: Revisar e discutir a literatura acerca do uso e da eficácia da PRF em exodontias de terceiros molares inferiores.  Metodologia: Foi realizado um levantamento bibliográfico mediante consulta às bases de dados PubMed, Web of Science, Scopus e Lilacs no período de outubro à novembro de 2020. Foram utilizados os seguintes descritores em conjunto: “platelet-rich fibrin”, “third molar” e “surgery”. A seleção dos artigos baseou-se no ano de publicação, restringindo-se aos últimos dez anos (2010 à 2020), ao idioma inglês, e aqueles em que o texto completo estava disponível. Foram selecionados os artigos que envolviam estudos de casos clínicos randomizados e revisões sistemáticas com e sem meta-análise acerca do uso da PRF após exodontias de terceiros molares inferiores. Foram excluídos os artigos que não se relacionavam ao tema proposto, além de revisões de literatura, artigos de opinião e relato de caso. Por fim, 24 artigos foram selecionados para a realização desta revisão de literatura. Resultados: Em relação a variante dor, 11 (45,8%) artigos mostraram em seus estudos diferenças significativamente estatísticas, 4 (16,6%) artigos não apresentaram diferenças e 9 (37,5%) artigos não relataram. Na variante edema, 10 (41,6%) artigos mostraram diferenças significativamente estatísticas; 3 (12,5%) artigos não apresentaram diferenças e 11 (45,8%) artigos não relataram. Na variante trismo, 1 (4,1%) artigo mostrou diferença significativamente estatística, 5 (20,8%) artigos não apresentaram diferenças e 18 (75%) artigos não relataram. Na variante reparo de tecido mole, 7 (29,1%) artigos mostraram diferenças significativamente estatísticas, 5 (20,8%) artigos não apresentaram diferenças e 12 (50%) não relataram. Por último, na variante reparo ósseo, 5 (20,8%) artigos mostraram diferenças significativamente estatísticas, 7 (29,1%) não apresentaram diferenças e 12 (50%) não relataram. Conclusão: Dessa forma, podemos observar que há a necessidade de mais estudos a fim de se obter resultados conclusivos sobre a real eficácia da PRF em exodontias de terceiros molares inferiores.

 

 


Keywords


Fibrina Rica em Plaquetas, Terceiro Molar, Cirurgia.

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DOI: https://doi.org/10.34119/bjhrv4n2-235

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