Análise da Incidência e das Relações entre as Principais Doenças Reumatológicas em Pacientes com Câncer de Mama: Uma Revisão Integrativa / Analysis of the Incidence and Relationships between the Main Rheumatological Diseases in Patients with Breast Cancer: An Integrative Review

Camila Adrielle Santos Cunha, Ana Luiza Rabelo de Castro, Ermônio Ernani Estanislau Oliveira, Júlia Gonçalves dos Santos, Marília Davoli Abella Goulart

Abstract


Introdução: As doenças reumatológicas e o câncer de mama compartilham a patogênese influenciada pela desregulação imunológica que desencadeiam uma inflamação crônica, sendo importante estabelecer uma relação entre ambas doenças devido à alta morbimortalidade que possuem quando acometidas simultaneamente. Objetivo: Estabelecer a incidência e as principais relações entre as doenças reumatológicas e o câncer de mama. Método: Consiste em uma revisão integrativa da literatura, realizado a partir de artigos publicados entre os anos de 2009 a 2020, por meio de uma busca eletrônica nas bases de dados: LILACS, SciELO e PubMed. Resultados: Foram selecionados 10 artigos de acordo com os critérios de elegibilidade. Em quatro artigos selecionados para a pesquisa, as doenças autoimunes mais comuns encontradas nos pacientes com câncer de mama foram: artrite reumatoide, síndrome de sjogren e lúpus eritematoso sistêmico. Em dois estudos a síndrome de sjogren foi a doença autoimune mais comum e em três estudos, a artrite reumatóide foi a patologia mais frequente. Estudos revisados apontaram que pacientes do sexo feminino com câncer de mama apresentam menor risco de apresentar lúpus eritematoso sistêmico, artrite rematóide e síndrome de sjogren quando comparadas às do sexo feminino sem câncer de mama, além de não haver uma relação específica entre o câncer de mama e o lúpus eritematoso sistêmico. Conclusão: Pacientes com doenças autoimunes apresentam menor risco de câncer de mama; sendo a artrite reumatoide, a síndrome de sjogren e o lúpus eritematoso sistêmico, as doenças reumatológicas mais frequentes em mulheres com neoplasia de mama.


Keywords


Doenças Reumáticas, Lúpus Eritematoso Sistêmico, Síndrome de Sjogren, Artrite Reumatoide, Câncer de Mama.

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DOI: https://doi.org/10.34119/bjhrv4n2-218

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