Efeito da Aplicação da energia vermelha monocromática (MIRE®) sobre a cicatrização de feridas cutâneas em ratos diabéticos / Monochromatic infrared energy application effect (MIRE®) of skin healing wounds in diabetic rats

Authors

  • Felipe Scipião Moura Brazilian Journals Publicações de Periódicos, São José dos Pinhais, Paraná
  • Francisco Valmor Macedo Cunha
  • Leonel Marques Rodrigues
  • Amanda Mota da Silva
  • Ana Marcelina Scipião Moura
  • Oséas Florêncio de Moura Filho
  • Maria do Carmo de Carvalho e Martins

DOI:

https://doi.org/10.34119/bjhrv4n2-147

Keywords:

Phototherapy, Wound Healing, Diabetes Mellitus

Abstract

Introduction: The monochromatic infrared energy use (MIRE®) as a resource to promote healing shows excellent prospects. Objective:  Determine the MIRE (890nm) application effect  in skin wounds healing in diabetic rats. Methods: Experimental type study, with qualitative and quantitative sample data  evaluation. Skin wounds 1 cm2  were made in the dorsal region Rattus norvegicus diabetics, who were randomly distributed in 14 animals  groups  and treated for seven to 14 days with 0.9% saline (control group - C) phototherapy (MIRE - wavelength = 890 nm; energy density = 24,96J / cm2; and irradiation time = 600 seconds) or clostebol acetate / neomycin sulfate (Trofodermin® - Default). Comparisons between groups were performed by ANOVA followed by post-Newman-Keuls test. Results: No statistically significant differences were found between the groups in the wounds contraction on the 4th day after wounds production. There was significantly higher wound contraction (p <0.05) in  standard group (0.66 ± 0.02) compared to MIRE® (0.27 ± 0.03) and control (0.43 ± 0, 07) on the 7th monitoring day. On  14th  treatment day, the wound contraction was higher (p <0.05) in standard group (0.87 ± 0.04) and MIRE® (0.81 ± 0.04) compared with control (0 68 ± 0.06). A semi-quantitative histological analysis revealed increased vascular proliferation in MIRE®. Conclusion: The results indicate that treatment with MIRE® favored the open wounds  healing in diabetic rats.

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Published

2021-03-18

How to Cite

MOURA, F. S.; CUNHA, F. V. M.; RODRIGUES, L. M.; DA SILVA, A. M.; MOURA, A. M. S.; FILHO, O. F. de M.; MARTINS, M. do C. de C. e. Efeito da Aplicação da energia vermelha monocromática (MIRE®) sobre a cicatrização de feridas cutâneas em ratos diabéticos / Monochromatic infrared energy application effect (MIRE®) of skin healing wounds in diabetic rats. Brazilian Journal of Health Review, [S. l.], v. 4, n. 2, p. 5839–5851, 2021. DOI: 10.34119/bjhrv4n2-147. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/26590. Acesso em: 28 mar. 2024.

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Section

Original Papers