Fotobiomodulação na prevenção e tratamento de sintomas neurológicos decorrentes da COVID-19: perspectivas a partir da literatura científica / Photobiomodulation in the prevention and treatment of neurological symptoms arising from COVID-19: perspectives from scientific literature

Bruno Sant’ Ana Costa, Guilherme de Aguiar Moraes, Cecília Tavares Borges, Daiane Thais Meneguzzo, Vivian de Oliveira Sousa Corrêa

Abstract


A pandemia por COVID-19 trouxe muitas perguntas, mas poucas apresentam respostas. Médicos e pesquisadores afirmam que o vírus causa uma reação exagerada do sistema imunológico conhecida como "tempestade de citocinas”. Sabe-se do alto tropismo do vírus pelo aparelho respiratório, mas sintomas neurológicos também são relatados em pacientes infectados. A fotobiomodulação (PBM) refere-se ao uso de lasers para modular uma função biológica. Buscou-se levantar informações a partir de bancos de dados científicos e analisar se a PBM pode ser utilizada como ferramenta para prevenção e tratamento de sintomas neurológicos consequentes da infecção pela COVID-19. Os autores pesquisaram no PubMed, MEDLINE, BVS, LILACS e Scielo artigos sobre fotobiomodulação e efeitos do COVID-19 no Sistema Nervoso. Os descritores utilizados foram "Photobiomodulation","COVID-19","neurological damage", "neurological disease", "neurological impacts" e “Neurological effects”. Foram encontrados 85 artigos na base PubMED e LILACS. As outras plataformas não apresentaram dados. Trabalhos com mais de 15 anos de publicação e que não estavam disponibilizados para acesso na íntegra foram excluídos. 46 trabalhos foram analisados,  incluindo-se no estudo apenas artigos inéditos ou de revisão. Observou-se que a PBM vem sendo estudada em variados cenários de patologias neurológicas com apresentações clínicas diversas, que perpassam desde os distúrbios da cognição e emoção, metabolismo, inflamação e fluxo sanguíneo cerebral, até os traumas e a performance motora. No entanto, nenhum dos artigos trazem relação direta da PBM com o tratamento ou prevenção de sintomas neurológicos decorrentes de infecção por COVID-19. Utilizar a PBM pode funcionar como uma nova janela terapêutica para a prevenção e tratamento de pacientes com COVID-19, evitando infecções crônicas no SN e danos neurológicos maiores a longo prazo.


Keywords


“Fotobiomodulação”, “COVID-19”, “Sistema Nervoso”, “Danos Neurológicos”.

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DOI: https://doi.org/10.34119/bjhrv4n2-117

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