A correlação entre o vírus da imunodeficiência humana e demência na terceira idade / The correlation between the human immunodeficiency virus and dementia in old age

Authors

  • Geovana Braz Nascimento
  • Marco Túlio Batista Vaz Filho
  • Ayla Solano Marques
  • Alexandre Rodrigues Ferreira de Oliveira
  • Lo-ruama Porto Viana
  • Isabelly Sousa Dias
  • Ester de Oliveira Teixeira
  • Maria Flávia Campos Adelino
  • Lucas Buozi Gonçalves Girotti
  • Matheus Henrique Santos Cardoso
  • Hellen Rodrigues Teixeira Silva Daameche

DOI:

https://doi.org/10.34119/bjhrv4n1-178

Keywords:

Demência, HIV, Idoso.

Abstract

Introdução: A demência causa processos neurodegenerativos graduais e, quando associada a replicação sistêmica do Vírus da Imunodeficiência Humana (HIV), predispõe um pior prognóstico devido à produção de déficits maiores na memória verbal. Objetivos: analisar as informações sobre a correlação entre o HIV e a demência na terceira idade, elucidando os aspectos fisiopatológicos e clínicos da doença. Metodologia: A revisão bibliográfica, de estudos publicados nos últimos 5 anos, utilizou como descritores “Demência” e “HIV’’, para então integrar os estudos dos indexadores MEDLINE e LILACS. Posteriormente, um artigo indexado no Google Scholar foi adicionado para complementação da literatura. Resultados: Vinte e quatro estudos foram selecionados, dos quais 20 estão indexados na base de dados da MEDLINE, três no LILACS e um no Google Scholar, sendo que dentre os artigos escolhidos seis foram revisões bibliográficas, seis estudos de Coorte, seis ensaios clínicos, dois estudos observacionais, dois estudos de rastreamento e dois retrospectivos. Conclusão: Concluiu-se que o sistema nervoso central é o principal alvo das disfunções neurocognitivas associadas ao HIV, com avaliação clínica de difícil execução e possuindo como terapia mais indicada para tratamento a terapia antiretroviral combinada devido sua capacidade de diminuição da carga viral no organismo do paciente infectado.

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Published

2021-01-28

How to Cite

NASCIMENTO, G. B.; FILHO, M. T. B. V.; MARQUES, A. S.; OLIVEIRA, A. R. F. de; VIANA, L.- ruama P.; DIAS, I. S.; TEIXEIRA, E. de O.; ADELINO, M. F. C.; GIROTTI, L. B. G.; CARDOSO, M. H. S.; DAAMECHE, H. R. T. S. A correlação entre o vírus da imunodeficiência humana e demência na terceira idade / The correlation between the human immunodeficiency virus and dementia in old age. Brazilian Journal of Health Review, [S. l.], v. 4, n. 1, p. 2198–2211, 2021. DOI: 10.34119/bjhrv4n1-178. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/23938. Acesso em: 29 mar. 2024.

Issue

Section

Original Papers