Implicações da microbiota intestinal humana no processo de obesidade e emagrecimento: revisão sistemática/Implications of the human gut microbiota in obesity and weight loss: systematic review

Authors

  • Joab Oliveira Salomão
  • Ian Dimas Cabral
  • Maria Olímpia Ribeiro do Vale Almada
  • Geilton Xavier de Matos
  • Monise Martins da Silva
  • Paulo Loivo do Nascimento
  • Rene Jesus de La Torre Acosta

DOI:

https://doi.org/10.34119/bjhrv3n5-301

Keywords:

Microbiota intestinal humana, obesidade, emagrecimento, modulação intestinal, probióticos.

Abstract

Introdução: Na última década foram produzidos vários trabalhos que identificaram a população microbiana intestinal humana como um dos braços do projeto Microbioma e posteriormente mais estudos que associaram populações específicas de microorganismos a determinadas funções e processos metabólicos no organismo, entre as diversas vertentes de estudo ressalta-se aqui a influência da microbiota no processo de obesidade e emagrecimento. Objetivo: Realizar revisão sistemática da literatura sobre as implicações da microbiota intestinal humana na gênese da obesidade e no processo de emagrecimento. Materiais e métodos: Revisão sistemática realizada entre agosto e setembro de 2020, de acordo os critérios PRISMA. Utilizou-se das bases de dados PubMed, Scientific Electronic Library Online (SciELO) e Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) para a pesquisa. Adotou-se exclusivamente o idioma inglês e apenas produções dos últimos 10 anos, com os seguintes termos e operadores: (Human Gut microbiota and obesity  OR dysbiosis and obesity OR human microbiota and weight loss). Resultados: Dos 16.917,000 artigos encontrados, selecionou-se um total de 53 artigos de melhor qualidade que respondessem as perguntas de pesquisa. Conclusão: Modificações da microbiota intestinal humana é capaz de contribuir para a gênese da obesidade, onde filos específicos de microorganismos são associados à maior absorção de energia, processos fermentativos, alterações no metabolismo da glicose e do colesterol, entre outras vias. Assim como os trabalhos que utilizaram da modulação da microbiota intestinal, seja através de modificações dietéticas ou uso de probióticos isoladamente e em conjunto demonstram efetividade no processo de emagrecimento e maior perda de peso sustentada em longo prazo.

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Published

2020-10-25

How to Cite

SALOMÃO, J. O.; CABRAL, I. D.; ALMADA, M. O. R. do V.; MATOS, G. X. de; SILVA, M. M. da; NASCIMENTO, P. L. do; ACOSTA, R. J. de L. T. Implicações da microbiota intestinal humana no processo de obesidade e emagrecimento: revisão sistemática/Implications of the human gut microbiota in obesity and weight loss: systematic review. Brazilian Journal of Health Review, [S. l.], v. 3, n. 5, p. 15215–15229, 2020. DOI: 10.34119/bjhrv3n5-301. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/18755. Acesso em: 29 mar. 2024.

Issue

Section

Original Papers