O papel da vitamina d na infecção pelo Coronavírus sars-cov-2: Revisão da literatura / The role of vitamin d in the sars-cov-2 Coronavirus infection: Literature review

Caroline Calixto Barros Sampaio Fernandes, Cintia Caroline Nunes Rodrigues, Gabriel Noé Albuquerque Paffer Cruz, Jamylla Correia de Almeida Costa, Maria Gabriel Rocha Melo, Tainá Ribas Pessôa, Leyna Leite Santos

Abstract


Atualmente o mundo está enfrentando uma das maiores pandemias com o SARS-CoV-2, e é notório que existem países no qual a mortalidade é maior que em outros. Dentre alguns fatores correlacionados está a hipovitaminose D, possível agravante do quadro desta afecção. Assim, o presente estudo objetiva compreender qual o papel da vitamina D na COVID-19. Realizou-se revisão integrativa da literatura nas bases de dados Medline, Scielo e Lilacs, com uso dos descritores e operador booleano AND. Foram selecionados 19 artigos e, dentre esses, foram observados diversos ensaios clínicos e metanálises que associam que o nível adequado desta vitamina pode reduzir infecções respiratórias por atuar na modulação da imunidade e interferir nas funções das proteínas do SARS-CoV-2. Todavia, não há evidências estabelecidas sobre a suplementação de vitamina D como prevenção da COVID-19, sendo imprescindível seu uso sob supervisão médica e realização de mais estudos para esclarecimento das lacunas existentes.


Keywords


Vitamina D, Covid-19, Eficiência, Terapêutica, Viroses.

References


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DOI: https://doi.org/10.34119/bjhrv3n4-150

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