Estudo de coorte prospectiva de pacientes com câncer de colo de útero: a idade é um fator determinante? / Prospective cohort study of cervical cancer patients: is age a determining factor?

Ana Carolina Vieira Selva, Carlos Vinícius Pacheco dos Santos Guarana, Victor de Souza Dias, Jurema Telles Sales, Carla Rameri Alexandre Silva de Azevedo

Abstract


Introdução: O câncer de colo de útero (CCU) apresenta alta prevalência e mortalidade. No Brasil, é a terceira causa mais comum de câncer no grupo feminino, acometendo também a população idosa. Objetivo: Delinear a epidemiologia de pacientes jovens e idosas com câncer de colo de útero e avaliar a eficácia do tratamento desse câncer no Instituto de Medicina Integral Prof. Fernando Figueira. Método: A partir de 2015, iniciou-se uma coorte de pacientes geriátricos em paralelo a outra coorte de pacientes com câncer de colo de útero. Este trabalho é o resultado da análise retrospectiva, específica de pacientes com câncer de colo de útero extraídas de ambas as coortes citadas. Foram coletados os dados demográficos, sobre os sintomas iniciais, estadiamento na ocasião do diagnóstico, tempo de início dos sintomas até o estabelecimento do diagnóstico, tempo do diagnóstico até o início do tratamento, sobrevida livre de doença e sobrevida global. Resultados: Foram incluídas 120 pacientes em ambas as coortes. Dentre estas, 73 tinham o diagnóstico de CCU e dados suficientes. Escolaridade e multiparidade mostraram efeitos significativos, sendo o analfabetismo e paridade de quatro a seis fatores de risco para o câncer de colo, especialmente entre o grupo de idosas. Ambos os grupos realizaram quimioterapia concomitante à radioterapia, tendo as adultas maior percentual de óbito em relação às idosas, ainda que esta diferença não tenha sido significativa. Conclusão: Este estudo observou que o principal resultado histopatológico foi de carcinoma escamoso e o estadiamento mais comum foi o III, refletindo um tratamento principalmente quimioterápico, com uma sobrevida estatisticamente semelhante entre os dois grupos.

 


Keywords


Neoplasias do colo do útero; Epidemiologia; Diagnóstico; Resultado do tratamento; Idoso.

References


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DOI: https://doi.org/10.34119/bjhrv3n4-115

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