Mental disorders and blood pressure changes in young adults / Transtornos mentais e mudanças na pressão de sangue em jovens adultos

Nathalia Luiza de Souza Leite, Fernanda Santos Portela, Lucimara da Silva Meira, Lorrane Carvalho Santana, Eduardo Freitas Rêgo, Laura Virgínia Prazeres Cotrim, Caio Matheus da Rocha Couqueiro Monteiro, Iaggo Raphael David


Background: Currently, mental disorders are being considered a worldwide problem that has affected individuals on a global scale. The physiological aspects that comprise these pathologies can infer changes in blood pressure, increasing the risk for the development of arterial hypertension. Objective: The present study aims to evaluate the influence of mental disorders and environmental factors for the development of changes in blood pressure that can progress to arterial hypertension in young adults of both genders. Materials and methods: This is a quantitative, observational, transversal, descriptive and experimental research in a city in the interior of Bahia. The sample consisted of 258 individuals, being 174 females and 84 males. Mental disorders (anxiety, depression and stress), physical activity, smoking and drinking habits, body fat and sociodemographic variables were analyzed. The data were tabulated and processed in the Excel program and subsequently transferred to the statistical program SPSS® 25.0., and the 95% significance level was considered. Initially, the descriptive analysis of the data was performed, then, the linear regression test was used to analyze the relationship of the variables and for that purpose two adjustment models were created. Model 1 - blood pressure (dependent variable), the variables of mental disorders (stress, anxiety and depression) and age; and in Model 2 its was inserted - physical activity, body fat, social class, marital status, education, drinking, smoking and work. Both models were applied according to gender. Results: The sample consisted of 127 women and 57 men whose ages varied from 29.03 (± 6.454) and 29.37 (± 6.44) for women and men, respectively. Table 1 shows the characteristics of the sample, blood pressure levels ranged from 114.98 (± 14.888) and 129.13 (± 17.915) for women and men, respectively. Table 2 shows the results of the linear regression according to the models mentioned in the methodology for both genders, in adjustment model 1 and 2, p≤0,000 was found for both genders. Final considerations: The importance of studying factors of mental and environmental risks consists of analyzing their influence on the individual's blood pressure and other possible illnesses, since the individual is a set of complexities and the environment in which he is inserted influences to health.


Major Depressive Disorder, Stress, Anxiety, Chronic diseases, Arterial hypertension.


ABESO, A. B. para E. da O., MANCINI, M. C. "Diretrizes brasileiras de obesidade 2016", VI Diretrizes Brasileiras de Obesidade, p. 7–186, 2016. DOI: 10.1590/S1415-52732000000100003. .

ANCHUELO, A. C., MARTÍNEZ-LARRAD, M. T., SERRANO-GARCÍA, Í., et al. "Body fat anthropometric indexes: Which of those identify better high cardiovascular risk subjects? A comparative study in Spanish population", PLoS ONE, v. 14, n. 5, p. 1–13, 2019. DOI: 10.1371/journal.pone.0216877. .

BEANEY, T., SCHUTTE, A. E., TOMASZEWSKI, M., et al. "May Measurement Month 2017: an analysis of blood pressure screening results worldwide", The Lancet Global Health, n. 18, p. 1–8, 2018. DOI: 10.1016/S2214-109X(18)30259-6. .

BUNDY, J. D., HE, J. "Hypertension and Related Cardiovascular Disease Burden in China", Annals of Global Health, v. 82, n. 2, p. 227–233, 2016. DOI: 10.1016/j.aogh.2016.02.002.

BYAMBASUKH, O., EISENGA, M. F., GANSEVOORT, R. T., et al. "Body fat estimates from bioelectrical impedance equations in cardiovascular risk assessment: The PREVEND cohort study", European Journal of Preventive Cardiology, v. 26, n. 9, p. 905–916, 2019. DOI: 10.1177/2047487319833283.

CAROLINA, A., AGUIRRE, C. "Depressão , ansiedade e hipertensão : qual a correlação ? Como melhorar o tratamento ?", Revista Brasileira de Hipertensão, v. 22, n. 1, p. 18–20, 2015. .

CORREIRA, T. A., GUIMARÃES, L. A., DIAS, Í. S., et al. "THE PRESENCE OF MENTAL DISORDERS IN HYPERTENSIONS WHAT OR NOT THE USE OF THE MEDICINE FOR CONTROL OF BLOOD PRESSURE", International Journal of Current Research, v. 11, n. 06, p. 4294–4297, 2019. DOI: Disponível em:

DAVID, I. R., GUIMARÃES, L. A., COSTA, M. M. L., et al. "the Framingham Heart Study-Hypertension: Systematic Review", International Journal of Development Research, v. 09, n. 10, p. 30665–30669, 2019. Disponível em:

DAVID, I. R., SILVA, M. L., SILVA, D. S., et al. "HYPERTENSION IS MULTIFACTORIAL!", International Journal of Development Research, v. 08, n. 10, p. 23490–23495, 2018.

DEPALMA, S. M., HIMMELFARB, C. D., MACLAUGHLIN, E. J., et al. "Hypertension guideline update", Journal of the American Academy of Physician Assistants, p. 1, maio 2018. DOI: 10.1097/01.JAA.0000533656.93911.38. .

DI GIOSIA, P., GIORGINI, P., STAMERRA, C. A., et al. "Gender Differences in Epidemiology, Pathophysiology, and Treatment of Hypertension", Current Atherosclerosis Reports, v. 20, n. 3, 2018. DOI: 10.1007/s11883-018-0716-z. .

DORADO, A. S., SANTOS, V. N., SANTOS, A. K. F., et al. "Epidemiological Profile of the Hypertensions", International Journal of Advanced Engineering Research and Science, v. 6, n. 5, p. 618–623, 2019. DOI: 10.22161/ijaers.6.5.78. .

DOUMAS, M., PAPADEMETRIOU, V., FASELIS, C., et al. "Gender differences in hypertension: Myths and reality", Current Hypertension Reports, v. 15, n. 4, p. 321–330, 2013. DOI: 10.1007/s11906-013-0359-y. .

GUBBELS BUPP, M. R. "Sex, the aging immune system, and chronic disease", Cellular Immunology, v. 294, n. 2, p. 102–110, 2015. DOI: 10.1016/j.cellimm.2015.02.002. .

GUSTAVSON, K., KNUDSEN, A. K., NESVÅG, R., et al. "Prevalence and stability of mental disorders among young adults: Findings from a longitudinal study", BMC Psychiatry, v. 18, n. 1, p. 1–15, 2018. DOI: 10.1186/s12888-018-1647-5. .

HERT, M. De, DETRAUX, J., VANCAMPFORT, D. "The intriguing relationship between coronary heart disease and mental disorders", Translational research, p. 31–40, 2018. .

HOSSEINI, M., YOUSEFIFARD, M., BAIKPOUR, M., et al. "Twenty-year dynamics of hypertension in Iranian adults: Age, period, and cohort analysis", Journal of the American Society of Hypertension, v. 9, n. 12, p. 925–934, 2015. DOI: 10.1016/j.jash.2015.09.005. .

HU, L., HUANG, X., YOU, C., et al. "Prevalence and risk factors of prehypertension and hypertension in Southern China", PLoS ONE, v. 12, n. 1, p. 1–15, 2017. DOI: 10.1371/journal.pone.0170238. .

LI, Z., FU, C., YANG, F., et al. "Prevalence and risk factors of hypertension for the middle-aged population in China — results from the China Health and Retirement Longitudinal Study (CHARLS)", Clinical and Experimental Hypertension, v. 00, n. 00, p. 1–7, 2018. DOI: 10.1080/10641963.2018.1445751. .

MUCCI, N., GIORGI, G., CERATTI, S. D. P., et al. "Anxiety, stress-related factors, and blood pressure in young adults", Frontiers in Psychology, v. 7, n. October, p. 1–10, 2016. DOI: 10.3389/fpsyg.2016.01682. .

NISHIO, S., MARUYAMA, Y., SUGANO, N., et al. "Gender interaction of uric acid in the development of hypertension", Clinical and Experimental Hypertension, v. 00, n. 00, p. 1–6, 2017. DOI: 10.1080/10641963.2017.1392556. .

OPARIL, S., ACELAJADO, M. C., BAKRIS, G. L., et al. "Hypertension", Nature Reviews Disease Primers, v. 4, 2018. DOI: 10.1038/nrdp.2018.14. .

PICHÉ, M. E., POIRIER, P., LEMIEUX, I., et al. "Overview of Epidemiology and Contribution of Obesity and Body Fat Distribution to Cardiovascular Disease: An Update", Progress in Cardiovascular Diseases, v. 61, n. 2, p. 103–113, 2018. DOI: 10.1016/j.pcad.2018.06.004. Disponível em:

PUZSEROVA, A., BERNATOVA, I. "Blood pressure regulation in stress: Focus on nitric oxide-dependent mechanisms", Physiological Research, v. 65, p. S309–S342, 2016. DOI: 10.33549/physiolres.933442. .


RECKELHOFF, J. F. "Gender differences in hypertension", Current Opinion in Nephrology and Hypertension, v. 27, n. 3, p. 176–181, 2018. DOI: 10.1097/MNH.0000000000000404.

SANTANA, A. R. A. A., SOUSA, B. R., LOPES, A. O. S., et al. "Prevalence of Mental Disorder in Adults and Elderly", International Journal of Advanced Engineering Research and Science, v. 6, n. 5, p. 240–245, 2019. DOI: 10.22161/ijaers.6.5.31. .

SHIN, H. Y., SHIN, M. H., RHEE, J. A. "Gender differences in the association between self-rated health and hypertension in a Korean adult population", BMC Public Health, v. 12, n. 1, p. 135, 2012. DOI: 10.1186/1471-2458-12-135. .

SOCIEDADE BRASILEIRA DE CARDIOLOGIA. "7a Diretriz Brasileira De Hipertensão Arterial", v. 107, 2016. .

UCHASOVA, E., GRUZDEVA, O., BARBARASH, O., et al. "Localization of fat depots and cardiovascular risk", Lipids in Health and Disease, 2018. DOI: 10.1186/s12944-018-0856-8. .

ZHANG, H., DENG, M., XU, H., et al. "Pre- and undiagnosed-hypertension in urban Chinese adults: A population-based cross-sectional study", Journal of Human Hypertension, v. 31, n. 4, p. 263–269, 2017. DOI: 10.1038/jhh.2016.73. .



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