Patients with genetic disorders as risk group for COVID-19 / Pacientes com distúrbios genéticos como grupo de risco para COVID-19

Lília Maria de Azevedo Moreira, Renata Melo dos Santos


The coronavirus disease (COVID-19) pandemic has seriously affected the global population and has raised concerns about the effect of this new disease on individuals with genetic disorders, many of which have a systemic effect, including impairment of the respiratory system. A lack of published literature about the consequences of  SARS-CoV-2 infection in genetic disorders is observed, in this sense,  the present review analyses the current knowledge about COVID-19 and its impacts on patients with genetic disorders, also genetic variants as factors of susceptibility and possible risks and preventive measures to those patients, highlighting the role of the restriction to social contact in prevention.


COVID-19, SARS-CoV-2, genetic variations, respiratory impairment, genetic disorders, risk group, social distancing measures.

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