Development and evaluation of organic silicon nanoparticles/ Desenvolvimento e avaliação de nanopartículas de silício orgânico

Rosana Letícia da Rosa, Luana Serbai, Robson Schimandeiro Novak, Josiane de Fátima Padilha de Paula, Ana Cristina Oltramari Toledo, Vanessa Von Mühlen de Carvalho, Patricia Mathias Döll Boscardin


Skin is an important component of outer beauty, it is the focus of many surgical and non-surgical procedures. Skin changes associated with intrinsic or extrinsic aging, such as wrinkles, sagging and pigmentation changes, can cause people to look for cosmetic procedures to improve the appearance of their skin. Studies demonstrate the importance of organic silicon in the production of type I collagen. The present work aimed to study the development of Silicium P® polymer nanoparticles. The suspension of nanoparticles was obtained by the technique of double emulsification-evaporation of the solvent where the physicochemical characterization was performed. These presented mean diameter of 562 nm, zeta potential of -37.2 mV and polydispersity index of 0.42. It was also obtained the infrared spectrum with Fourier transform where it showed that there were no molecular interactions that alter the chemical structures of the components of the formulation during the process of obtaining the nanoparticles.



Collagen; Silicium P®; Skin aging; Nanoparticle.

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